The beta-lactam backbone

The aminopenicillins are a group of antibiotics[1] in the penicillin family -- as such, they contain a beta-lactam ring, and inhibit the synthesis of bacterial cell walls.

Aminopenicillins feature a positively-charged amino group that enhances their uptake through bacterial porin channels. This does not, however, confer resistance to bacterial beta-lactamases. [2] Members of this family include ampicillin, amoxicillin, and bacampicillin.[3]

See also


  1. ^ Cunha BA (August 1992). "Aminopenicillins in urology". Urology 40 (2): 186–90.  
  2. ^ Golan, David E. Principles of Pharmacology. Philadelphia, PA: Lippincott Williams & Wilkins.  
  3. ^ "Mayo Clinic Proceedings". Retrieved 2008-12-26.