Normethadone

Normethadone

Normethadone
Systematic (IUPAC) name
6-dimethylamino-4,4-diphenyl-hexan-3-one
Clinical data
Trade names Cophylac
Legal status
Identifiers
CAS number  N
847-84-7 (HCl)
ATC code R05
PubChem
ChemSpider  Y
UNII  Y
KEGG  Y
ChEMBL  Y
Chemical data
Formula C20H25NO 
Mol. mass 295.419 g/mol
 N   

Normethadone (INN, BAN; brand names Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent.[1] Similarly to methadone, normethadone has a long duration and a slow onset of action, and is approximately between one- and two-thirds as potent in comparison.

Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and resultantly is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grammes.

Synthesis

Normethadone synthesis:[2]

See also

References

  1. ^ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 711. ISBN . Retrieved 17 May 2012. 
  2. ^ Duprè, D. J.; Elks, J.; Hems, B. A.; Speyer, K. N.; Evans, R. M. (1949). "113. Analgesics. Part I. Esters and ketones derived from α-amino-ω-cyano-ωωdiarylalkanes". Journal of the Chemical Society (Resumed) (Chemical Society): 500. doi:10.1039/JR9490000500.