Levodropropizine

Levodropropizine

Levodropropizine
Systematic (IUPAC) name
(2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
Clinical data
AHFS/Drugs.com
Legal status
?
Pharmacokinetic data
Protein binding 11-14%
Excretion 83% via urine within 96 h
Identifiers
CAS number  Y
ATC code R05
PubChem
ChemSpider  Y
UNII  Y
KEGG  Y
ChEBI  N
Chemical data
Formula C13H20N2O2 
Mol. mass 236.31 g/mol
 N   

Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system.[1] It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives.

References

  1. ^ De Blasio, F.; Dicpinigaitis, P. V.; Rubin, B. K.; De Danieli, G.; Lanata, L.; Zanasi, A. (2012). "An observational study on cough in children: Epidemiology, impact on quality of sleep and treatment outcome". Cough 8 (1): 1. PMC 3274450. PMID 22269875. doi:10.1186/1745-9974-8-1.