Homocitric acid

Homocitric acid

Homocitric acid
CAS number
Jmol-3D images Image 1
Molecular formula C7H10O7
Molar mass 206.15 g mol−1
Appearance Colorless solid
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Homocitric acid is an tricarboxylic acid occurs naturally as a component of the iron-molybdenum cofactor of certain nitrogenase proteins.[1] Biochemists often refer to this cofactor as homocitrate, which is the conjugate bases that predominate in neutral aqueous solutions of this species.

The molecule is related to citric acid by the addition of one methylene unit, hence the prefix "homo." Unlike citric acid, homocitric acid is chiral. The acid exists in equilibrium with the lactone.

See also


  1. ^ Rees, Douglas C. (2002). "Greatmetalloclustersinenzymology". Annual Review of Biochemistry 71: 221–46.