Haloprogin

Haloprogin

Haloprogin
Systematic (IUPAC) name
1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
Clinical data
Legal status
  • Not available in U.S.
Routes of
administration
Topical
Identifiers
CAS Registry Number  YesY
ATC code D01
PubChem CID:
DrugBank  YesY
ChemSpider  YesY
UNII  YesY
KEGG  YesY
ChEMBL  YesY
Chemical data
Formula C9H4Cl3IO
Molecular mass 361.39 g/mol
Physical data
Melting point 113.5 °C (236.3 °F)
Solubility in water insoluble mg/mL (20 °C)
 YesY   

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.[1]

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[2]

References

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