Dihydrodipicolinate reductase

dihydrodipicolinate reductase
EC number CAS number IntEnz BRENDA ExPASy KEGG MetaCyc metabolic pathway
PRIAM PDB structures PDBsum
Gene Ontology EGO

In chemical reaction

(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ \rightleftharpoons 2,3-dihydrodipicolinate + NAD(P)H + H+

The 3 substrates of this enzyme are (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate, NAD+, and NADP+, whereas its 4 products are 2,3-dihydrodipicolinate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate:NAD(P)+ oxidoreductase. Other names in common use include dihydrodipicolinic acid reductase, and 2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase. This enzyme participates in lysine biosynthesis.

Structural studies

As of late 2007, 11 1YL7.