Dense granules

Dense granule
Latin granulum delta
Code Template:TerminologiaHistologica

Dense granules (also known as dense bodies or delta granules) are specialized secretory organelles.

In unicellular organisms

They are found in animals and in unicellular organisms including Apicomplexa protozoans.

They are also found in Entamoeba.[1]

In multicellular organisms

Components

The dense granules of human platelets contain adenosine diphosphate (ADP), adenosine triphosphate (ATP), ionized calcium (which is necessary for several steps of the coagulation cascade), histamine and serotonin.[2]

Clinical significance

A deficiency of CD63 can be associated with Hermansky-Pudlak syndrome.[3]

See also

References