Carbocisteine

Carbocisteine

Carbocisteine
Identifiers
CAS number  (R) Y,  (RS)
PubChem
ChemSpider  Y
DrugBank
KEGG  Y
ChEBI  Y
ChEMBL  Y
ATC code R05
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C5H9NO4S
Molar mass 179.19 g mol−1
Appearance Colorless solid
Melting point 204 to 207 °C (399 to 405 °F; 477 to 480 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N?)
Carbocisteine molecule, in 3D

Carbocisteine is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.

Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.[1]

Trade names

Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam[2]

Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.

Mucoral: Portugal

Mucosol: Egypt

Solmux, Loviscol: Philippines

Humotusin: Romania

References

  1. ^ Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in Ullmann's Encyclopedia of Industrial Chemistry, 2007, Wiley-VCH, Weinheim. doi:10.1002/14356007.a02_057.pub2
  2. ^ http://www.drugs.com/international/rhinathiol.html