CLEC10A

CLEC10A

C-type lectin domain family 10, member A
Identifiers
Symbols  ; CD301; CLECSF13; CLECSF14; HML; HML2; MGL
External IDs GeneCards:
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

C-type lectin domain family 10 member A also known as CLEC10A is a protein that in humans is encoded by the CLEC10A gene.[1]

Function

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.[2]

References

  1. ^ Suzuki N, Yamamoto K, Toyoshima S, Osawa T, Irimura T (January 1996). "Molecular cloning and expression of cDNA encoding human macrophage C-type lectin. Its unique carbohydrate binding specificity for Tn antigen". J. Immunol. 156 (1): 128–35.  
  2. ^ "Entrez Gene: CLEC10A C-type lectin domain family 10, member A". 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.