Benorilate

Benorilate

Benorilate
Systematic (IUPAC) name
4-(acetylamino)phenyl 2-(acetyloxy)benzoate
Clinical data
Routes of
administration
Oral
Identifiers
CAS Registry Number  N
ATC code N02
PubChem CID:
ChemSpider  N
UNII  Y
ChEMBL  N
Chemical data
Formula C17H15NO5
Molecular mass 313.305 g/mol
 N   

Benorilate (INN), or benorylate, is an ester-linked codrug of aspirin with paracetamol. It is used as an anti-inflammatory and antipyretic medication. In the treatment of childhood fever, it has been shown to be inferior to paracetamol and aspirin taken separately. In addition, because it is converted to aspirin, benorylate is not recommended in children due to concerns about Reye syndrome.[1]

References

  1. ^ Simila S, Keinanen S, Kouvalainen K.Oral antipyretic therapy: evaluation of benorylate, an ester of acetylsalicylic acid and paracetamol. Eur J Pediatr. 1975 Dec 9;121(1):15-20. PMID 2478