Bacteriostatic agent

Bacteriostatic agent

A bacteriostatic agent or bacteriostat, abbreviated Bstatic, is a biological or chemical agent that stops bacteria from reproducing, while not necessarily killing them otherwise. Depending on their application, bacteriostatic antibiotics, disinfectants, antiseptics and preservatives can be distinguished. When bacteriostatic antimicrobials are used, the duration of therapy must be sufficient to allow host defense mechanisms to eradicate the bacteria. Upon removal of the bacteriostat, the bacteria usually start to grow again. This is in contrast to bactericides, which kill bacteria.[1]

Bacteriostats are often used in plastics to prevent growth of bacteria on surfaces. Bacteriostats commonly used in laboratory work include sodium azide (which is acutely toxic) and thiomersal (which is a mutagen in mammalian cells).

Bacteriostatic antibiotics

Bacteriostatic antibiotics limit the growth of bacteriocidal agents are bacteriostatic.

This group[2] includes

See also


  1. ^ Pankey GA, Sabath LD (March 2004). "Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram-positive bacterial infections". Clin. Infect. Dis. 38 (6): 864–70.  
  2. ^ Shetty N, Aarons E, Andrews J (2009). "Chapter 5: General principles of antimicrobial therapy". In Andrews J, Shetty N, Tang JW. Infectious Disease: Pathogenesis, Prevention and Case Studies. Wiley-Blackwell.